Article
Ex vivo generation of effective Epstein-Barr virus (EBV)-specific CD8+ cytotoxic T lymphocytes from the peripheral blood of immunocompetent Epstein Barr virus-seronegative individuals.
Transplantation - 27 Nov 2000
Metes D, Storkus W, Zeevi A, Patterson K, Logar A, Rowe D, Nalesnik M A, Fung J J, Rao A S
Abstract excerpt
BACKGROUND: Although readily accomplished from immunocompetent Epstein-Barr virus- (EBV) seropositive individuals, the effective ex vivo generation of EBV-specific cytotoxic T lymphocytes (CTL) from the peripheral blood mononuclear cells (PBMC) of EBV-seronegative subjects has proven to be a chal...
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