Article
Isolation and expansion of lymphocytes from gastrointestinal tumour tissue.
Surgical oncology - 1 Oct 1993
Somers S S, Guillou P J
Abstract excerpt
Adoptive cellular immunotherapy (ACI) with tumour-infiltrating lymphocytes (TIL) has met with some success in patients suffering from malignant melanoma. However, the success of this approach hinges on the successful isolation and in vitro expansion of TIL. Viable, IL-2 responsive TIL were obtained from only two of five gastrointestinal primary or 'non-lymph node' secondary gastrointestinal tumours. In contrast,...
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