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Article

Human peripheral blood xenografts in the SCID mouse: characterization of immunologic reconstitution.

The Journal of infectious diseases - 1 Sept 1993

Hesselton R M, Koup R A, Cromwell M A, Graham B S, Johns M, Sullivan J L

Abstract excerpt

Immune reconstitutions (hu-PBL-SCID mice) resulting from adoptive transfer of human peripheral blood mononuclear cells into 1800 C.B-17 scid-/scid-mice were characterized. Over 90% of reconstitutions were successful as evidenced by human immunoglobulin production. Variability was noted with donor, cell number, and cell type. Human cells (T lymphocytes, few B cells) could be recovered by 5 days after engraftment....

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Identifiers

PMID: 8354904
DOI: 10.1093/infdis/168.3.630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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