Article
A cytotoxic T-lymphocyte clone derived from mice with progressively growing tumors.
Archives of surgery (Chicago, Ill. : 1960) - 1 Apr 1991
Hoover S K, Inge T H, Frank J L, McKinnon G, Monaco J, Susskind B, Bear H D
Abstract excerpt
Tumor-specific T-cell clones were derived from spleen cells of mice bearing a syngeneic PHS-5 tumor (a P815 mastocytoma mutant). Cells were expanded in vitro and characterized and assayed for activity against the relevant tumor in vivo. Clone cells were CD4-, CD8+ T lymphocytes, as determined by...
Topics
- Animals
- CD4-Positive T-Lymphocytes
- Clone Cells
- Immunotherapy, Adoptive
- Interleukin-2
- Liver Neoplasms
- Lymphocyte Activation
- Mice
- Mice, Inbred DBA
- Neoplasms, Experimental
- Phenotype
- Spleen