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Article

A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer.

Cancer immunology, immunotherapy : CII - 1 Mar 2003

Iwashita Yukio, Tahara Kouichirou, Goto Shigeru, Sasaki Atsushi, Kai Seiichiro, Seike Masataka, Chen Chao-Long, Kawano Katsunori, Kitano Seigo

Abstract excerpt

BACKGROUND/AIMS: To evaluate the safety and feasibility of immunotherapy based on autologous dendritic cells (DC) for patients with unresectable primary liver cancer (PLC). METHODS: A total of ten patients were enrolled and immunized with DCs. Autologous DCs were generated ex vivo in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4). Cells were then pulsed with...

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Identifiers

PMID: 12649744
DOI: 10.1007/s00262-002-0360-9
PMCID: PMC11032976

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TNF

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