Selectively down-regulated expression of major histocompatibility complex class I alleles in human solid tumors.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Selectively down-regulated expression of major histocompatibility complex class I alleles in human solid tumors.

Cancer research - 15 May 1993

Végh Z, Wang P, Vánky F, Klein E

Abstract excerpt

We studied the expression of major histocompatibility complex (MHC) class I molecule in 52 ex-vivo tumor samples comprising 29 ovarian, 15 lung, 1 breast, and 4 colon carcinomas; 1 midgut carcinoid; and 2 malignant mesenchymal tumors obtained from surgical specimens or from malignant effusions. T...

Topics

Alleles
Carcinoma, Squamous Cell
Down-Regulation
Female
Gene Expression Regulation, Neoplastic
Genes, MHC Class I
Humans
Interferon-gamma
Isoelectric Focusing
Lung Neoplasms
Lymphocytes
Ovarian Neoplasms
Recombinant Proteins
Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 8485728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8485728-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics