Article
The biological consequences of altered MHC class I expression in tumours.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Algarra I, Gaforio J J, Cabrera T, Collado A, Garrido F
Abstract excerpt
The identification of different mechanisms by which tumours escape from the immune system has helped to evaluate the clinical relevance of a variety of phenotypic changes that occur during tumour development. Among them, changes in HLA class I expression play a leading role in the tumour-host environment since HLA class I molecules interact with T lymphocytes for antigen presentation and with NK cells for...
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