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Article

Altered MHC class I antigens in tumors.

International journal of clinical & laboratory research - 1 Jan 1997

Algarra I, Collado A, Garrido F

Abstract excerpt

MHC class I antigens are lost or downregulated in invasive tumors compared with autologous normal tissues. This is observed in most of the newly induced experimental tumors analyzed if they are cloned before passaging in vivo. Similarly, this is observed in 40%-90% of human tumors using the available panel of anti-HLA class I monoclonal antibodies. In both systems the tumor populations are heterogeneous for...

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Identifiers

PMID: 9266279
DOI: 10.1007/BF02912442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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