Article
Altered MHC class I antigens in tumors.
International journal of clinical & laboratory research - 1 Jan 1997
Algarra I, Collado A, Garrido F
Abstract excerpt
MHC class I antigens are lost or downregulated in invasive tumors compared with autologous normal tissues. This is observed in most of the newly induced experimental tumors analyzed if they are cloned before passaging in vivo. Similarly, this is observed in 40%-90% of human tumors using the avail...
Topics
- Animals
- Antigens, Neoplasm
- Histocompatibility Antigens Class I
- Humans
- Killer Cells, Natural
- Mice
- Phenotype
- Sarcoma, Experimental
- T-Lymphocytes