High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas.

doi:10.1111/j.1399-0039.1998.tb02274.x

Back to search

Article

High frequency of altered HLA class I phenotypes in invasive colorectal carcinomas.

Tissue antigens - 1 Aug 1998

Cabrera T, Collado A, Fernandez M A, Ferron A, Sancho J, Ruiz-Cabello F, Garrido F

Abstract excerpt

We analyzed the expression of HLA class I antigens in 78 tumor tissue samples obtained from patients diagnosed as having colorectal carcinomas. A broad panel of mAbs defining HLA monomorphic, locus-specific and allele-specific determinants was used. In addition, an antibody defining HLA-C locus-s...

Topics

Alleles
Amino Acid Sequence
Antibodies, Monoclonal
Carcinoma
Colorectal Neoplasms
Gene Expression Regulation, Neoplastic
Haplotypes
Histocompatibility Antigens Class I
Humans
Immunophenotyping
Molecular Sequence Data
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.