Article
Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier.
Virology - 1 May 1993
Fernholz D, Galle P R, Stemler M, Brunetto M, Bonino F, Will H
Abstract excerpt
All human hepatitis B viruses characterized so far express three envelope proteins, pre-S1, pre-S2, and HBs, which are believed to function as binding proteins for the cellular receptor, as targets for immune-mediated virus elimination, and in virion morphogenesis and secretion. Here we report th...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- Carrier State
- Cells, Cultured
- Cloning, Molecular
- Gene Expression Regulation, Viral
- Genetic Variation
- Genome, Viral
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Surface Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Hepatitis, Chronic
- Humans
- Liver
- Male