Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Properties of hepatitis B virus pre-S1 deletion mutants.

Virology - 1 Mar 1994

Melegari M, Bruno S, Wands J R

Abstract excerpt

Deletion mutants of hepatitis B virus (HBV) pre-S proteins were detected in serum in 2 of 10 (20%) individuals with chronic hepatitis B infection following the initiation of interferon treatment. The size of these deletions was up to one-half of the entire pre-S1 region. In vivo, all HBV deletion mutants were found to coexist with a full-length "wild-type" viral genome. The functional properties of a HBV-deleted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B virus
Share to Base Sequence
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Molecular Sequence Data

Share to Mutation

Share to Protein Precursors

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8122362
DOI: 10.1006/viro.1994.1127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Properties of hepatitis B virus pre-S1 deletion mutants.PMID 8122362Read ↗

The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deletedSemantic proximity Read ↗

Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma.Semantic proximity Read ↗

Prevalence and significance of hepatitis B virus (HBV) pre-S mutants in serum and liver at different replicative stages of chronic HBV infection.Semantic proximity Read ↗

Pre-S mutations of hepatitis B virus affect genome replication and expression of surface antigens.Semantic proximity Read ↗

Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma.Semantic proximity Read ↗

Infection process of the hepatitis B virus depends on the presence of a defined sequence in the pre-S1 domain.Semantic proximity Read ↗

Hepatitis B Virus Pre-S Gene Deletions and Pre-S Deleted Proteins: Clinical and Molecular Implications in Hepatocellular CarcinomaSemantic proximity Read ↗

Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier.Semantic proximity Read ↗

Hepatitis B virus pre-S/S variants in liver diseases.Semantic proximity Read ↗

Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigen-negative individuals.Semantic proximity Read ↗

Profile of pre-S deletions in the natural history of chronic hepatitis B infection.Semantic proximity Read ↗

Full-length sequence and functional analysis of hepatitis B virus genome in a virus carrier: a case report suggesting the impact of pre-S and core promoter mutations on the progression of the disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.