Article
Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigen-negative individuals.
Hepatology (Baltimore, Md.) - 1 Jul 2005
Hass Meike, Hannoun Charles, Kalinina Tatyana, Sommer Gunhild, Manegold Christoph, Günther Stephan
Abstract excerpt
The biological properties of latent or occult hepatitis B virus (HBV) have been poorly characterized as a result of the extremely low virus concentration. This report describes the phenotype of HBV reactivating in two patients after an HBsAg-negative latency period. One patient had latent HBV infection for at least 12 years without detectable viremia and symptoms of liver disease. Several full-length HBV genomes...
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