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Article

Rapid kinetics of mismatch repair of heteroduplex DNA that is formed during recombination in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1993

Haber J E, Ray B L, Kolb J M, White C I

Abstract excerpt

Homothallic switching of yeast mating type (MAT) genes is a highly efficient gene conversion process initiated by a double-strand break. The use of a galactose-inducible HO endonuclease gene has made it possible to analyze the synchronous progression of molecular intermediates during recombination. When MATa switches to MAT alpha, a 3' single-stranded end of HO-cleaved MAT DNA invades the homologous donor, HML...

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Identifiers

PMID: 8475081
DOI: 10.1073/pnas.90.8.3363
PMCID: PMC46300

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