Article

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor.

1993-06-01

Abstract excerpt

Moloney murine leukemia virus causes thymic leukemias when injected into newborn mice. A major determinant of the thymic disease specificity of Moloney virus genetically maps to the conserved viral core motif in the Moloney virus enhancer. Point mutations introduced into the core site significantly shifted the disease specificity of the Moloney virus from thymic leukemia to erythroid leukemia (N.A. Speck, B. Renji...

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Literature Corpus work: 8e3d5871-d2f4-534f-865f-fc718e242a6b
DOI: 10.1128/mcb.13.6.3324

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