Article
c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer.
Molecular and cellular biology - 1 Jun 1995
Hernandez-Munain C, Krangel M S
Abstract excerpt
A T-cell-specific transcriptional enhancer lies within the J delta 3-C delta intron of the human T-cell receptor delta gene. We have previously shown that a 30-bp element, denoted delta E3, acts as the minimal TCR delta enhancer and that within delta E3, adjacent and precisely spaced binding site...
Topics
- Base Sequence
- Cell Line
- Core Binding Factors
- DNA-Binding Proteins
- Drug Synergism
- Enhancer Elements, Genetic
- Humans
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-myb
- Receptors, Antigen, T-Cell, gamma-delta
- Signal Transduction
- T-Lymphocytes
- Transcription Factors