Article
Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene.
Kidney international. Supplement - 1 Jan 1993
Yang C W, Striker L J, Kopchick J J, Chen W Y, Pesce C M, Peten E P, Striker G E
Abstract excerpt
Mice transgenic for bovine growth hormone (bGH) develop an increase in body weight and glomerular lesions characterized by a disproportionate increment in glomerular volume and progressive mesangial sclerosis. The relationship between glomerular size and body growth in bGH mice was further invest...
Topics
- Animals
- Cattle
- Cell Division
- Collagen
- Glomerulosclerosis, Focal Segmental
- Growth Hormone
- Kidney Glomerulus
- Mice
- Mice, Transgenic
- Mutation
- RNA, Messenger