Article
Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene.
Kidney international. Supplement - 1 Jan 1993
Yang C W, Striker L J, Kopchick J J, Chen W Y, Pesce C M, Peten E P, Striker G E
Abstract excerpt
Mice transgenic for bovine growth hormone (bGH) develop an increase in body weight and glomerular lesions characterized by a disproportionate increment in glomerular volume and progressive mesangial sclerosis. The relationship between glomerular size and body growth in bGH mice was further investigated by examining mice transgenic for a mutated GH gene (bGH-m11) which failed to enhance body growth. The glomeruli...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
