Studies by competitive PCR of glomerulosclerosis in growth hormone transgenic mice.

Article

Studies by competitive PCR of glomerulosclerosis in growth hormone transgenic mice.

Kidney international. Supplement - 1 Jan 1993

Peten E P, Striker L J, Garcia-Perez A, Striker G E

Abstract excerpt

We have shown that the glomerulosclerotic lesions of mice transgenic for bovine growth hormone (bGH mice) consisted of a change in the phenotype of glomerular collagens and an elevation of the mRNAs for these collagens in whole kidney. The purpose of this study was to determine whether these phen...

Topics

Animals
Collagen
Gene Expression Regulation
Glomerulosclerosis, Focal Segmental
Growth Hormone
Kidney Glomerulus
Mice
Mice, Transgenic
Phenotype
Polymerase Chain Reaction
RNA, Messenger

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