Article
Expression of mutant bovine growth hormone genes in mice perturbs age-related nutrient utilization patterns.
The Journal of nutrition - 1 Mar 1998
Turner N D, Knapp J R, Byers F M, Kopchick J J
Abstract excerpt
Three lines of transgenic mice expressing mutant bovine growth hormone (bGH) genes and displaying small (G119K), near normal (M11) or large (M4) phenotypes and nontransgenic control (NTC) mice were used to determine GH-associated, age-specific changes in empty body composition. The single amino acid substitution in G119K mice reduced the quantities (P < 0.001) and early rates (P < 0.05) of deposition for water,...
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