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Article

Noncomplementary DNA double-strand-break rejoining in bacterial and human cells.

Nucleic acids research - 11 Mar 1993

King J S, Valcarcel E R, Rufer J T, Phillips J W, Morgan W F

Abstract excerpt

We examined the rejoining of noncomplementary restriction enzyme-produced DNA double-strand breaks in Escherichia coli and in cultured human cells. The enzymes used in this study, ClaI, BamHI and SalI, produce double-strand breaks with 5 protruding single strands. The joining of a ClaI-produced D...

Topics

Base Composition
Base Sequence
DNA Damage
DNA Repair
DNA, Bacterial
Deoxyribonuclease BamHI
Deoxyribonucleases, Type II Site-Specific
Escherichia coli
Humans
Molecular Sequence Data
Mutation
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transformation, Bacterial

Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 8464692
DOI: 10.1093/nar/21.5.1055
PMCID: PMC309262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8464692-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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