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Article

Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replication

1 Jun 1992

Abstract excerpt

We have localized a cis-acting sequence that promotes initiation of lytic-phase DNA replication (oriLyt) within the HindIII D fragment of the human cytomegalovirus (HCMV) AD169 genome and investigated its sequence requirements by testing the ability of plasmid constructs to mediate DNA replication in a transient transfection-plus-infection assay. Replication of plasmids containing HCMV oriLyt required at least...

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PMID: 1316454
DOI: 10.1128/jvi.66.6.3373-3384.1992

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Boundaries and structure of human cytomegalovirus oriLyt, a complex origin for lytic-phase DNA replicationPMID 1316454Read ↗

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Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesisSemantic proximity Read ↗

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