Article
Chromosomal circularization in Streptomyces griseus by nonhomologous recombination of deletion ends.
Bioscience, biotechnology, and biochemistry - 1 May 2003
Inoue Shoichi, Higashiyama Koji, Uchida Tetsuya, Hiratsu Keiichiro, Kinashi Haruyasu
Abstract excerpt
Streptomyces linear chromosomes frequently cause deletions at both ends spontaneously or by various mutagenic treatments, and concomitantly display dynamic structural changes such as circularization and arm replacement. We have cloned and sequenced the fusion junctions of circularized chromosomes in two deletion mutants of Streptomyces griseus. No homology and a 1-bp overlap were found between the deletion ends...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
