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Article

The human low affinity immunoglobulin G Fc receptor IIC gene is a result of an unequal crossover event.

1 Apr 1993

Abstract excerpt

We have isolated and characterized three genes coding for hFc gamma RIIA, IIB, and IIC. Each gene spans approximately 15-19 kilobases of DNA and consists of eight exons. Two exons encode the 5'-untranslated region and signal peptides, two exons code for homologous Ig-like extracellular domains, a single exon encodes the transmembrane spanning region, and three exons encode the cytoplasmic domains and...

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PMID: 8463268
DOI: 10.1016/s0021-9258(18)53181-1

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