Article

The Human Fibroblast Growth Factor Receptor Genes: a Common Structural Arrangement Underlies the Mechanisms for Generating Receptor Forms That Differ in Their Third Immunoglobulin Domain

1991-09-01

Abstract excerpt

To determine the mechanisms by which multiple forms of fibroblast growth factor (FGF) receptors are generated, we have mapped the arrangement of exons and introns in the human FGF receptor 1 (FGFR 1) gene (flg). We found three alternative exons encoding a portion of the third immunoglobulin (Ig)-like domain of the receptor. One of these alternatives encodes a sequence that is part of a secreted form of FGFR 1. The...

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Literature Corpus work: a8dc2f30-eff9-5fe2-87ae-211a894d74b4
DOI: 10.1128/mcb.11.9.4627-4634.1991

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