Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Divergence of human alpha-chain constant region gene sequences. A novel recombinant alpha 2 gene.

1 Jun 1994

Abstract excerpt

IgA is the major Ig synthesized in humans and provides the first line of defense at the mucosal surfaces. The constant region of IgA heavy chain is encoded by the alpha gene on chromosome 14. Previous studies have indicated the presence of two alpha genes, alpha 1 and alpha 2, with alpha 2 existing in two allotypic forms, alpha 2 m(1) and alpha 2 m(2). Here we report the cloning and complete nucleotide sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Immunodeficiency and Autoimmune Disorders
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8189047
DOI: 10.4049/jimmunol.152.11.5299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Divergence of human alpha-chain constant region gene sequences. A novel recombinant alpha 2 gene.PMID 8189047Read ↗

New alleles of human immunoglobulin kappa J segments IGKJ2 and IGKJ4.Semantic proximity Read ↗

The human low affinity immunoglobulin G Fc receptor IIC gene is a result of an unequal crossover event.Semantic proximity Read ↗

Cloning and structural analysis of two highly divergent IgA isotypes, IgA1 and IgA2 from the duck billed platypus, Ornithorhynchus anatinus.Semantic proximity Read ↗

Expression cloning of a human Fc receptor for IgA.Semantic proximity Read ↗

Intraspecies heterogeneity of immunoglobulin alpha-chain constant region genes in rhesus macaques.Semantic proximity Read ↗

IgA in the horse: cloning of equine polymeric Ig receptor and J chain and characterization of recombinant forms of equine IgASemantic proximity Read ↗

The constant region genes of the immunoglobulin heavy chains.Semantic proximity Read ↗

Expression and secretion of immunoglobulin alpha heavy chain with diverse VDJ recombinations by human epithelial cancer cellsSemantic proximity Read ↗

Identification of four allelic variants of the dog IGHA gene.Semantic proximity Read ↗

Human IgG2 Antibodies Display Disulfide-mediated Structural IsoformsSemantic proximity Read ↗

Sequence of the CH1 and hinge-CH2 exons of the human immunoglobulin IGHA2 A2m(2) allele: comparison with the nonallelic and allelic IGHA genes.Semantic proximity Read ↗

RFLP of human immunoglobulin genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.