Article
Characteristics and significance of albumin-positive hepatocytes in analbuminemic rats.
European journal of cell biology - 1 Dec 1990
Tanaka H, Matsuhisa A, Nagamori S, Shimizu K, Niiya M, Ohno T, Nagase S
Abstract excerpt
Analbuminemic rats (NAR) are a mutant strain in which splicing of the albumin mRNA is blocked due to a seven-base-pair deletion in an intron of the albumin gene. NAR liver contains a few hepatocytes that react with anti-rat albumin antibody (Alb+ hepatocytes), and these cells increase in number d...
Topics
- Albumins
- Animals
- Blotting, Western
- Female
- Immunohistochemistry
- Liver
- Mutation
- RNA, Messenger
- Rats
- Rats, Mutant Strains
- Serum Albumin
- p-Dimethylaminoazobenzene