Article
Expression of mutant ELH prohormones in AtT-20 cells: the relationship between prohormone processing and sorting.
The Journal of cell biology - 1 Apr 1993
Jung L J, Kreiner T, Scheller R H
Abstract excerpt
Posttranslational processing of many proteins is essential to the synthesis of fully functional molecules. The ELH (egg-laying hormone) prohormone is cleaved by endoproteases in a specific order at a variety of basic residue processing sites to produce mature peptides. The prohormone is first cle...
Topics
- Amino Acid Sequence
- Animals
- Antibody Specificity
- Aplysia
- Base Sequence
- Cell Line
- Cloning, Molecular
- DNA
- Fluorescent Antibody Technique
- Immunohistochemistry
- Invertebrate Hormones
- Mice
- Molecular Sequence Data
- Mutation
- Precipitin Tests
- Protein Precursors
- Protein Processing, Post-Translational
- Time Factors