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Article

Expression of mutant ELH prohormones in AtT-20 cells: the relationship between prohormone processing and sorting.

The Journal of cell biology - 1 Apr 1993

Jung L J, Kreiner T, Scheller R H

Abstract excerpt

Posttranslational processing of many proteins is essential to the synthesis of fully functional molecules. The ELH (egg-laying hormone) prohormone is cleaved by endoproteases in a specific order at a variety of basic residue processing sites to produce mature peptides. The prohormone is first cleaved at a unique tetrabasic site liberating two intermediates (amino and carboxy) which are sorted to different classes...

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Identifiers

PMID: 8458863
DOI: 10.1083/jcb.121.1.11
PMCID: PMC2119775

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Source receipt: pubmed, retrieved 7 Sept 2026.

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