Article
Peptide hormone precursor processing: getting sorted?
Molecular and cellular endocrinology - 25 Oct 1999
Canaff L, Bennett H P, Hendy G N
Abstract excerpt
Processing of proproteins to biologically active peptides and, in the case of peptide hormones and neuropeptides, their sorting to granules of the regulated secretory pathway, requires the concerted action of a cascade of enzymes and chaperones. The purpose of this review is to summarize the recent emerging knowledge of how these molecules affect specific endocrine systems. This has come about through the study...
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