Article
Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants.
Genetics - 1 Oct 2015
Gáliková Martina, Diesner Max, Klepsatel Peter, Hehlert Philip, Xu Yanjun, Bickmeyer Iris, Predel Reinhard, Kühnlein Ronald P
Abstract excerpt
Maintenance of biological functions under negative energy balance depends on mobilization of storage lipids and carbohydrates in animals. In mammals, glucagon and glucocorticoid signaling mobilizes energy reserves, whereas adipokinetic hormones (AKHs) play a homologous role in insects. Numerous studies based on AKH injections and correlative studies in a broad range of insect species established the view that AKH...
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