Article
Expression and post-translational processing of gastrin in heterologous endocrine cells.
The Journal of biological chemistry - 5 Apr 1991
Marino L R, Takeuchi T, Dickinson C J, Yamada T
Abstract excerpt
The biosynthesis of gastrin involves a complex series of post-translational processing reactions that result in the formation of a biologically active secretory product. To study the mechanisms for two specific reactions in gastrin processing, namely dibasic cleavage and amidation, we infected AtT-20, GH3, and Rin5-f cells with the retroviral expression vector, pZip-NeoSV(X), containing human gastrin cDNA. We...
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