Article
Expression and post-translational processing of gastrin in heterologous endocrine cells.
The Journal of biological chemistry - 5 Apr 1991
Marino L R, Takeuchi T, Dickinson C J, Yamada T
Abstract excerpt
The biosynthesis of gastrin involves a complex series of post-translational processing reactions that result in the formation of a biologically active secretory product. To study the mechanisms for two specific reactions in gastrin processing, namely dibasic cleavage and amidation, we infected At...
Topics
- Animals
- Base Sequence
- Cell Line
- Chromatography, Gel
- DNA
- Dexamethasone
- Endocrine Glands
- Gastrins
- Gene Expression Regulation, Viral
- Genes, Viral
- Genetic Vectors
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational
- Rats
- Retroviridae
