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Article

Molecular analysis of dibasic endoproteolytic cleavage signals.

The Journal of biological chemistry - 25 Oct 1992

Dickinson C J, Daugherty D, Guo Y J, Hughes P, Yamada T

Abstract excerpt

Biologically active peptide hormones are synthesized from larger precursor proteins by a variety of post-translational processing reactions. To characterize these processing reactions further we have expressed preprogastrin in two endocrine cell lines and examined the molecular determinants involved in endoproteolysis at dibasic cleavage sites. The Gly93-Arg94-Arg95 carboxyl-terminal processing site of progastrin...

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Identifiers

PMID: 1400488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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