Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Article

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

American journal of human genetics - 1 Mar 1993

Spielman R S, McGinnis R E, Ewens W J

Abstract excerpt

A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1" alleles of the region of tandem-repeat DNA (5' flanking polymorphism [5'FP]) adjacent to the insulin gene on chromosome 11p. This finding suggests that the insulin gene reg...

Topics

Adult
Alleles
Analysis of Variance
Child
Diabetes Mellitus, Type 1
Family
Female
Genetic Carrier Screening
Genetic Markers
Humans
Insulin
Linkage Disequilibrium
Male
Mathematics
Repetitive Sequences, Nucleic Acid

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