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Article

Testing linkage disequilibrium in sibships.

American journal of human genetics - 1 Jul 2000

Siegmund K D, Langholz B, Kraft P, Thomas D C

Abstract excerpt

We describe the use of multivariate regression for testing allelic association in the presence of linkage, using marker genotype data from sibships. The test is valid, provided that the correct mean structure is modeled but does not require the correlation structure within families to be specified. The test can be implemented using standard statistical software such as the SAS programming language. In a...

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Identifiers

PMID: 10831398
DOI: 10.1086/302973
PMCID: PMC1287084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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