Evolution of bacteriophage T7 in a growing plaque.

doi:10.1128/jb.175.5.1272-1277.1993

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Article

Evolution of bacteriophage T7 in a growing plaque.

Journal of bacteriology - 1 Mar 1993

Yin J

Abstract excerpt

The emergence of mutants during the 10(9)-fold amplification of a bacteriophage was spatially resolved in a growing plaque. When wild-type phage T7 was grown on an Escherichia coli host which expressed an essential early enzyme of the phage infection cycle, the T7 RNA polymerase, mutant phage rel...

Topics

Bacteriophage T7
Biological Evolution
DNA-Directed RNA Polymerases
Escherichia coli
Genetic Variation
Genotype
Kinetics
Mutation
Phenotype
Selection, Genetic
Viral Plaque Assay
Viral Proteins

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