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Article

In vivo analysis of the initiation of bacteriophage T7 DNA replication.

Virology - 1 Feb 1990

Rabkin S D, Richardson C C

Abstract excerpt

We have examined the initiation of bacteriophage T7 DNA replication in vivo using a pulse-labeling technique. The pulse-labeling technique permits the rapid identification of initiation sites on the T7 chromosome and a determination of the rate of movement of the replication fork. This technique has been used to analyze a number of phage mutants having alterations in the nucleotide sequence of the primary origin....

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PMID: 2305553
DOI: 10.1016/0042-6822(90)90111-4

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