Article
In vivo analysis of the initiation of bacteriophage T7 DNA replication.
Virology - 1 Feb 1990
Rabkin S D, Richardson C C
Abstract excerpt
We have examined the initiation of bacteriophage T7 DNA replication in vivo using a pulse-labeling technique. The pulse-labeling technique permits the rapid identification of initiation sites on the T7 chromosome and a determination of the rate of movement of the replication fork. This technique has been used to analyze a number of phage mutants having alterations in the nucleotide sequence of the primary origin....
Topics
- DNA Replication
- DNA, Viral
- Mutation
- T-Phages
- Virus Replication