Article
Evolutionary design on a budget: robustness and optimality of bacteriophage T7.
Systems biology - 1 Mar 2006
You L, Yin J
Abstract excerpt
Exploring how biological systems have been 'designed' by evolution to achieve robust behaviours is now a subject of increasing research effort. Yet, it still remains unclear how environmental factors may contribute to this process. This issue is addressed by employing a detailed computer model for the intracellular growth of phage T7. More than 150 000 in silico T7 mutants were generated and the rates and...
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