Article
Meta-analysis identifies an association between the dopamine D2 receptor gene and schizophrenia.
Molecular psychiatry - 1 Nov 2003
Glatt S J, Faraone S V, Tsuang M T
Abstract excerpt
The D2 subtype of dopamine receptor has been widely implicated in the pathogenesis of schizophrenia. Early evidence supporting an association between the Cys311Ser polymorphism of the D2 receptor gene (DRD2) and schizophrenia was subsequently refuted and, eventually, dismissed. From all 24 published case-control studies, we calculated a pooled estimate of this association. The pooled odds ratio was 1.3 for the...
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