Article
An association study of DRD2 gene polymorphisms with schizophrenia in a Chinese Han population.
Neuroscience letters - 21 Jun 2010
Fan Hua, Zhang Fuquan, Xu Yong, Huang Xuezhu, Sun Gaoxiang, Song Yuqing, Long Haiyin, Liu Pozi
Abstract excerpt
Dopamine signaling is strongly implicated in the etiology of schizophrenia (SZ). Because of the essential role dopamine D2 receptor (DRD2) in dopamine signaling, DRD2 gene has been regarded as one of the top candidate genes for SZ. However, the findings from linkage and association analyses on this gene are mixed and largely inconsistent across various studies. The aim of this study is to investigate the...
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