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Article

The role of TREX in gene expression and disease

27 Sept 2016

Abstract excerpt

TRanscription and EXport (TREX) is a conserved multisubunit complex essential for embryogenesis, organogenesis and cellular differentiation throughout life. By linking transcription, mRNA processing and export together, it exerts a physiologically vital role in the gene expression pathway. In addition, this complex prevents DNA damage and regulates the cell cycle by ensuring optimal gene expression. As the extent...

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PMID: 27679854
DOI: 10.1042/bcj20160010

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