Article
BM2L is a spontaneous leukemogenic variant of a non-leukemogenic v-myb-transformed myeloid cell line.
Oncogene - 1 Mar 1993
Bottazzi M E, Goodenow M M, Moscovici M G, Moscovici C
Abstract excerpt
Leukemogenesis is a complex process involving an accumulation of genetic lesions affecting both growth and differentiation in cells of the hematopoietic lineage. Our laboratory has established a non-producer v-myb-transformed cell line (BM2/C3A) which, when injected into the chicken embryo, does...
Topics
- Alleles
- Animals
- Base Sequence
- Cell Adhesion
- Cell Differentiation
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Chick Embryo
- Leukemia, Monocytic, Acute
- Molecular Sequence Data
- Oncogene Proteins v-myb
- Oncogenes
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-myb
- Retroviridae Proteins, Oncogenic
