Biological properties and growth in SCID mice of a new myelogenous leukemia cell line (KBM-5) derived from chronic myelogenous leukemia cells in the blastic phase.

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Article

Biological properties and growth in SCID mice of a new myelogenous leukemia cell line (KBM-5) derived from chronic myelogenous leukemia cells in the blastic phase.

Cancer research - 1 Aug 1993

Beran M, Pisa P, O'Brien S, Kurzrock R, Siciliano M, Cork A, Andersson B S, Kohli V, Kantarjian H

Abstract excerpt

The establishment and the biological properties of a new leukemic cell line (KBM-5) derived from a patient in the blastic phase of chronic myelogenous leukemia are described. The cells exhibited multiple copies of the Philadelphia chromosome, and a high level of p210Bcr-Abl kinase activity was de...

Topics

Aged
Animals
Base Sequence
Blast Crisis
Cell Differentiation
Chromosome Aberrations
Cytokines
Female
Fusion Proteins, bcr-abl
Humans
Isoenzymes
Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Mice

Mice, SCID

Molecular Sequence Data

Phenotype

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8339266

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8339266-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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