Article
Conditional mutations in the yeast DNA primase genes affect different aspects of DNA metabolism and interactions in the DNA polymerase alpha-primase complex.
Genetics - 1 Feb 1993
Longhese M P, Jovine L, Plevani P, Lucchini G
Abstract excerpt
Different pri1 and pri2 conditional mutants of Saccharomyces cerevisiae altered, respectively, in the small (p48) and large (p58) subunits of DNA primase, show an enhanced rate of both mitotic intrachromosomal recombination and spontaneous mutation, to an extent which is correlated with the sever...
Topics
- Alleles
- DNA Polymerase II
- DNA Primase
- DNA Repair
- DNA Replication
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Meiosis
- Mitosis
- Mutation
- Protein Binding
- RNA Nucleotidyltransferases
- Recombination, Genetic
- Saccharomyces cerevisiae
- Spores, Fungal