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Article

Escherichia coli K-12 has two distinguishable PriA-PriB replication restart pathways.

Molecular microbiology - 1 Oct 2021

Sandler Steven J, Leroux Maxime, Windgassen Tricia A, Keck James L

Abstract excerpt

In Escherichia coli, PriA, PriB, PriC, and DnaT proteins mediate three pathways for Replication Restart called PriA-PriB, PriA-PriC, and PriC. PriA is crucial for two of the three pathways. Its absence leads to slow growth, high basal levels of SOS expression, poorly partitioning nucleoids, UV sensitivity, and recombination deficiency. PriA has ATPase and helicase activities and interacts with PriB, DnaT, and...

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Identifiers

PMID: 34423481
DOI: 10.1111/mmi.14802
PMCID: PMC8541903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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