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Article

ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes.

The Journal of biological chemistry - 5 Apr 1992

Zavitz K H, Marians K J

Abstract excerpt

The PriA replication protein of Escherichia coli (formerly replication factor Y or protein n') is multifunctional. It is a site-specific, single-stranded DNA-dependent ATPase (dATPase), a 3'----5' DNA helicase, and guides the ordered assembly of the primosome, a mobile, multiprotein DNA replication priming/helicase complex. Although PriA is not absolutely required for viability, priA null mutant cells grow very...

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PMID: 1313026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes.PMID 1313026Read ↗

Escherichia coli K-12 has two distinguishable PriA-PriB replication restart pathways.Semantic proximity Read ↗

The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair.Semantic proximity Read ↗

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ATPase/helicase motif mutants of Escherichia coli PriA protein essential for recombination-dependent DNA replication.Semantic proximity Read ↗

Mutational Analysis of Residues in PriA and PriC Affecting Their Ability To Interact with SSB in Escherichia coli K-12.Semantic proximity Read ↗

Restart of DNA replication in Gram-positive bacteria: functional characterisation of the Bacillus subtilis PriA initiator.Semantic proximity Read ↗

PriA mutations that affect PriA-PriC function during replication restart.Semantic proximity Read ↗

Purification and characterization of DnaC810, a primosomal protein capable of bypassing PriA function.Semantic proximity Read ↗

Crystal structure and DNA-binding mode of Klebsiella pneumoniae primosomal PriB protein.Semantic proximity Read ↗

Multiple genetic pathways for restarting DNA replication forks in Escherichia coli K-12.Semantic proximity Read ↗

Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replication.Semantic proximity Read ↗

Replication Restart in Bacteria.Semantic proximity Read ↗

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