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Article

Immunobiological studies on experimental visceral leishmaniasis. III. Cytokine-mediated regulation of parasite replication.

Scandinavian journal of immunology - 1 Feb 1993

Saha B, Basak S K, Roy S

Abstract excerpt

The role of T-cell-derived cytokines in the regulation of Leishmania donovani replication was studied in a murine model. It was observed that in H-2d mice at the early and later stages of the disease IFN-gamma-secreting T cells predominate, whereas in between the above stages IL-4-secreting T cells predominate. Possibly, IL-4 abrogates the protective ability of IFN-gamma and thereby exponential parasite growth is...

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PMID: 8434228
DOI: 10.1111/j.1365-3083.1993.tb01751.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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