A CD4+ TH2 cell line isolated from mice chronically infected with Trypanosoma cruzi induces IgG2 polyclonal response in vivo.

doi:10.1002/eji.1830200515

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Article

A CD4+ TH2 cell line isolated from mice chronically infected with Trypanosoma cruzi induces IgG2 polyclonal response in vivo.

European journal of immunology - 1 May 1990

Spinella S, Milon G, Hontebeyrie-Joskowicz M

Abstract excerpt

In our study we describe further characteristics of a CD4+ T cell line (G-05) isolated from lymph nodes of C3H/HeJ mice chronically infected with Trypanosoma cruzi. This T cell line secreted lymphokines such as interleukin (IL) 4 and IL 5 and could be defined as a TH2 type of helper T cells. By p...

Topics

Animals
B-Lymphocytes
CD4-Positive T-Lymphocytes
Cell Line
Chagas Disease
Immunization, Passive
Immunoglobulin G
Lymphokines
Mice
Mice, Inbred C3H
Phenotype
T-Lymphocytes, Helper-Inducer

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