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Article

Protective effect of leflunomide on the natural course of Leishmania major-induced disease in genetically susceptible BALB/c mice.

International journal of immunopharmacology - 1 Jun 1995

Solbach W, Asmuss P A, Zimmermann S, Humborg C, Röllinghoff M

Abstract excerpt

Leflunomide has been reported as an immunomodulating agent which acts on a variety of cells including T- and B-lymphocytes. CD4+ T-lymphocytes are essential for the type of disease that develops after infection with the protozoan parasite Leishmania major. A variety of immunological interventions has been shown to modulate disease development. Therefore, the effect of leflunomide on the development of...

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PMID: 7499024
DOI: 10.1016/0192-0561(95)00028-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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