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Article

IL-4 induces a Th2 response in Leishmania major-infected mice

1 Feb 1992

Abstract excerpt

The infection of mice with Leishmania major can cause either a fatal disseminated disease or a localized healing disease, depending on the genetic background of the mice. A strong correlation has been shown between disease outcome and the nature of the T cell response, with healer strains developing a Th1-like response and nonhealer strains a Th2-like response. The treatment of nonhealer BALB/c mice with a single...

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Identifiers

PMID: 1531351
DOI: 10.4049/jimmunol.148.4.1182

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