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Article

Expression of tyrosinase gene in transgenic mice: programmed versus non-programmed expression.

The Journal of investigative dermatology - 1 Feb 1993

Takeuchi T, Tanaka S, Tanaka M

Abstract excerpt

The transgenic experiment is a useful tool for the study of cell type-specific expression of genes during embryogenesis. We constructed a minigene, mg-Tyrs-J, by fusing a tyrosinase cDNA, Tyrs-J, with the 5' upstream region of genomic deoxyribonucleic acid (DNA) clone, G3L, and microinjected this minigene into fertilized eggs from albino BALB/c mice. It was expected that a melanin pigment would be produced and...

Topics

Animals
Cloning, Molecular
Crosses, Genetic
Female
Gene Expression
Mice
Mice, Transgenic
Monophenol Monooxygenase
Pedigree
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 8432999

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