Article
Rescue of the albino phenotype by introducing a functional tyrosinase minigene into Kunming albino mice.
World journal of gastroenterology - 14 Jan 2007
Xiao Dong, Yue Ying, Deng Xin-Yan, Huang Bing, Guo Zhong-Min, Ma Yun, Lin Yi-Li, Hong Xun, Tang Huan, Xu Kang, Chen Xi-Gu
Abstract excerpt
AIM: To use the tyrosinase minigene as a visual marker to perform microinjection training and improve the techniques related with transgene to greatly elevate the efficiency of gene transfer. METHODS: A mouse tyrosinase minigene, i.e., TyBS, in which the 2.25-kb authentic genomic 5' non-coding flanking sequence of mouse tyrosinase was fused to a mouse tyrosinase cDNA, was introduced into the fertilized eggs of...
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