Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.

doi:10.1161/01.atv.13.1.1

Back to search

Article

Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 1993

Mehrabian M, Qiao J H, Hyman R, Ruddle D, Laughton C, Lusis A J

Abstract excerpt

Previous studies have shown that distal mouse chromosome 1 contains the apolipoprotein AII (apoAII) gene, encoding the second most abundant apolipoprotein in high density lipoproteins (HDLs), as well as a gene termed Ath-1 that controls aortic fatty streak development and HDL cholesterol levels i...

Topics

Animals
Apolipoprotein A-II
Arteriosclerosis
Cholesterol, HDL
Chromosome Mapping
Genes
Genetic Variation
Lipoproteins, HDL
Mice
Mice, Inbred Strains
Recombination, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.